Mechanism of Action and Pharmacokinetics Drostanolone

Methyldrostenolone is a hormone synthesized from drostanolone and differs from it by the presence of a methyl group which gives it activity via oral administration. Oral bioavailability is estimated at 50%. It acts by stimulating protein synthesis, especially of cellular enzymes, which is done through specific androgenic receptors of the cellular cytoplasm, which generates an increase in muscle strength. It is a predominantly androgenic steroid, it can be used without the risk of increasing your estrogen levels.

 

Indications

Male hypogonadism, hematological disorder, hereditary angioneurotic edema, breast carcinoma, osteoporosis and catabolic states.

 

Posology

The dose is 10 mg – 20 mg per day in men, taken for no more than 6 or 8 weeks, if you miss the imitated dose as soon as possible, do not double the dose. If you have any questions, ask your doctor. In women an effective oral daily dose lasting no less than 4-6 weeks.

Contraindications

Its prolonged use is contraindicated due to the effects on the liver. It is very important to use a liver protector during consumption. If not used do not consume for more than two weeks.

Adverse reactions

Estrogenic side effects are minimal, because it does not convert estrogen, but many times when taken orally there may be a problem with gynecomastia due to the fact that it greatly reduces SHBG and increases TST. The most common are: acne, penis enlargement, increased erection frequency, irregular menstrual periods in women, abnormal hair growth or hair loss.

Restrictions of Use

The safety of the use of methandrostenolone during pregnancy and lactation is not well established, so suspension in use is recommended.

Overdose

Treatment in case of overdose: There have been no reports of overdose with the product.

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